The Recent History of Tumour Necrosis Factor (TNF)

The Recent History of Tumour Necrosis Factor (TNF)

‘… it was the age of innocence that Marc [Feldmann] and I enjoyed where we could actually talk freely about what we did … That kind of culture, sadly, has also been asphyxiated by the imposition of bureaucratic structures …’ Professor Sir Ravinder Nath (Tiny) Maini

With an introduction by Professor Jon Cohen, this Witness Seminar focuses on the recent history of TNF and its identification as a therapeutic target for rheumatoid arthritis and other diseases. The participants provide insights into how TNF has become a focal point for the study of inflammatory and malignant diseases, and discuss the obstacles and the opportunities that arose during the development of anti-TNF drugs.

Zarros A, Jones E M, and Tansey E M. (eds) (2016)
Wellcome Witnesses to Contemporary Medicine, vol. 60. London: Queen Mary University of London.
ISBN 978 1 91019 5208

‘… the work on anti-TNF has been exemplary for many other disciplines in medicine … This story is not only about the success of the anti-TNF trials, it’s the success of how to approach a medical problem and to deal with it with the most modern medicine that you can.’  Professor Yuti Chernajovsky